Grow Youthful: How to Slow Your Aging and Enjoy Extraordinary Health
Grow Youthful: How to Slow Your Aging and Enjoy Extraordinary Health

Candida

Fungi - the garbage collectors of dead cells

What is candida?

Candida fungicide resistance

What causes the excess dead cells that candida feed on?

Symptoms of a high dead cell load

Causes of candida overgrowth

The worst effects of candida

Symptoms of candida overgrowth

Prevention / remedies / cures / treatment for candida

References

Fungi - the garbage collectors of dead cells

Fungi are the garbage collectors of the microbiological world. They feed by secreting digestive enzymes into their surrounding environment, and then absorbing the dissolved organic matter. Fungi decompose and consume dead plants and animals, and are the principal cleaners in ecological systems. They are abundant everywhere, and especially in the soil. Fungi are easily able to digest cellulose (wood), keratin and virtually all other parts of animals that bacteria are not able to break down.

Yeasts are small, single celled members of the fungi kingdom. Yeasts are a normal and healthy component of your gut biome, your skin, and other parts of your body such as your mouth, genitals and nose.

Yeasts are also able to break down most sugars, except if the sugars are too pure and concentrated. This is why dry candied, sugar-crystallised fruits, sweets and treats have an almost indefinite shelf life unless they get wet, when yeasts and other types of fungi start to appear. When you eat these sweets and they are in liquid form in your digestive system, yeasts can proliferate on the sugar if there is no competition from other microorganisms to keep their numbers down.

A similar argument applies to dry, refined carbohydrates. Dry, white refined flour will last almost indefinitely, as will many of the products made from it. Dry pasta, dry bread, biscuits and cookies, dry snacks and breakfast cereals all have a long shelf life. After they are chewed and turned to liquid in the digestive tract, these simple starches and sugars are an attractive food to yeasts.

Yeasts also thrive on dead cells. If you have an overgrowth of yeasts (usually candida) in your body, they may be dining on decaying cells as opposed to sugars and starches. The cause of candida overgrowth is an overload of dead cells coming from somewhere in the body. Candida get an extra fuel boost if you are on a high-sugar and refined carbohydrate diet.

Before you can eliminate a candida overgrowth, you first have to stop the causes of accelerated cell death.

What is candida?

Candidiasis on tounge

Candida is a yeast, one of over 1000 microorganisms (bacteria, fungi and protozoa) (also called micro-flora) present in the intestines of a healthy person. These natural gut microbes are essential for the healthy functioning of your digestive system. They make vitamins, steroids and fatty acids, break down toxins, help to digest and absorb nutrients, and prevent the overgrowth of yeasts, parasites and bad bacteria.

There are many species of Candida and Candida-like yeasts, but only about twenty of them cause infections in humans. The most common species is Candida albicans, which can also cause infections in animals. C. albicans, C. tropicalis, C. parapsilosis, and C. glabrata are together responsible for the majority of cases of candidiasis in humans. Candidiasis is the name given to a fungal infection caused by one of the Candida species.

Candida albicans is a yeast that normally reproduces slowly, in a process called budding. If your gut is healthy, there is lots of competition between the different yeasts, bacteria and fungi, and the candida's reproduction is restricted. However, if the balance of micro-organisms in your gut is upset, the candida can proliferate out of control. The most frequent and damaging cause of candida overgrowth is antibiotics.

Candida fungicide resistance

Many species of fungi have evolved resistance to fungicides, in a similar manner that bacteria evolve resistance to antibiotics through the overuse of these pharmaceuticals. The overuse of fungicides has not been widely reported in the media, but it is just as serious as the overuse of antibiotics. Fungicides are also extensively used in agriculture and gardening, being routinely sprayed on plants. Doctors routinely prescribe fungicides, the most commonly used is fluconazole. (2, 3, 4)

The most common pharmaceutical drugs used to treat candidiasis are:
amphotericin B, echinocandin, voriconazole and fluconazole for systemic infections;
nystatin for oral and esophageal infections;
clotrimazole for skin and genital yeast infections.

Candida auris was first identified in 2009, but seems to be spreading rapidly around the world. It has emerged as the most fungicide-resistant of the candida which infect humans. More than 90% of C. auris are resistant to fluconazole, and they are increasingly resistant to other fungicides such as voriconazole.

C. auris causes severe illness and death in hospitalized patients. It can enter the bloodstream and spread throughout the body, causing serious invasive infections. This yeast often does not respond to commonly used antifungal drugs, making infections difficult to treat. Patients who have been hospitalized in a healthcare facility a long time, have a central venous catheter, or other lines or tubes entering their body, or have previously received antibiotics or antifungal medications, appear to be at highest risk of infection with this yeast.

Specialized laboratory methods are needed to accurately identify C. auris. Conventional laboratory techniques could lead to misidentification and inappropriate management, making it difficult to control the spread of C. auris in healthcare settings.

An outbreak of C. auris in a hospital and other healthcare facility requires thorough, expensive and time-consuming clean-up of the entire facility. A large-scale outbreak would be difficult to control and could spread quickly.

What causes the excess dead cells that candida feed on?

All cells in the body have a finite life. Cells lining the colon or the surface of the tongue only last a day or two before they die and are replaced. Skin cells are replaced every month, and red blood cells have a life of about three months. 98% of your entire body is replaced each year. Autophagy is the normal, healthy process of cellular death and clean up.

Many conditions increase the rate of cell death, or increase the number of dead cells that need cleaning up. A variety of illnesses, parasites, toxins and pharmaceutical medicines can quickly cause an overload of dead cells. The excess of dead cells causes an overgrowth of yeasts, as dead cells are yeast's primary food.

Symptoms of a high dead cell load

Causes of candida overgrowth

The worst effects of candida

Leaky gut. Antibiotics kill all the bacteria in your gut indiscriminately - the good and the bad. Good bacteria provide a protective gut barrier, preventing leaky gut. Candida is a yeast, not a bacterium and so is unharmed by the antibiotics. If you take antibiotics, as the bacteria die off there is suddenly little competition and the candida can reproduce rapidly. It changes its method of reproduction, producing tubes or rhizoids. These tubes penetrate your intestinal tissue and blood vessels, exposing your blood to yeasts and the by-products of digestion.

Allergies. In these circumstances, you are likely to develop allergies to the foods you eat most frequently. Your immune system sees the partially digested proteins in your blood as invaders (antigens), and responds by forming antibodies. The more you eat the food, the stronger the sensitivity or allergy reaction. The foods that candida sufferers most commonly react to are wheat, corn, soy and dairy products.

Tartaric acid is a metabolite (by product) of candida, produced during excessive fermentation. Tartaric acid interferes with the body's ability to produce energy aerobically using glucose. Instead, it produces a fifth of the energy anaerobically by converting glucose into lactic acid. High levels of tartaric acid body cause muscle weakness, leading to tiredness, chronic fatigue, fibromyalgia, overacidity and mineral deficiency so common with candida infections. This lack of energy also affects the brain, causing mental problems such as brain fog, depression, hyperactivity, autism and schizophrenia.

Other toxins. An overgrowth of candida (candidiasis or thrush) produces large amounts of two toxins - alcohol and acetaldehyde. The effects of alcohol are well known. It is possible for a teetotaller suffering from candida overgrowth to be drunk most of the time, especially if they are eating lots of fruit and sugars. Many cases of children and adults behaving as if they were drunk have cleared up after removing a candida colony. Candida can be devastating during the early stages of pregnancy, when the foetus is highly susceptible to alcohol.
Acetaldehyde affects brain function, making sufferers feel fuzzyheaded and unable to think clearly. The two toxins can cause mood swings and irrational behaviour.

Symptoms of candida overgrowth

Prevention / remedies / cures / treatment for candida

To eliminate candida, you have to do two things:

First, stop the over production of dead cells, dead bacteria, and excess waste organic matter. Grow Youthful has plenty of suggestions, depending on what the cause is in your particular case.

Second, stop fuelling the candida with a high sugar, high refined carbohydrate diet.

References

1. Roberto Vazquez-Munoz, Miguel Avalos-Borja, Ernestina Castro-Longoria. Ultrastructural Analysis of Candida albicans When Exposed to Silver Nanoparticles. PLoS One. 2014; 9(10). Published online 7 October 2014. doi: 10.1371/journal.pone.0108876. PMCID: PMC4188582. PMID: 25290909.

2. Lockhart Shawn R, Etienne Kizee A, Vallabhaneni Snigdha, Farooqi Joveria, Chowdhary Anuradha, Govender Nelesh P, Colombo Arnaldo Lopes, Calvo Belinda, Cuomo Christina A. Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses. Clinical Infectious Diseases. 15 January 2017. 64 (2): 134-140. doi:10.1093/cid/ciw691. PMC 5215215. PMID 27988485.

3. Chowdhary et al. Multidrug-resistant endemic clonal strain of Candida auris in India. Eur J Clin Microbiol Infect Dis. 33:919-26.

4. Rudramurthy et al. Candida auris candi- daemia in Indian ICUs: analysis of risk factors. J Antimicrob Chemother 2017; 72:1794-801.