Grow Youthful: How to Slow Your Aging and Enjoy Extraordinary Health
Grow Youthful: How to Slow Your Aging and Enjoy Extraordinary Health

Kidney disease (renal failure or nephropathy) and polycystic kidney disease (PKD)

What is kidney disease?

Symptoms of kidney disease

Causes of kidney disease

Prevention / remedies / cures / treatment for kidney disease

References

What is kidney disease?

The kidneys are two organs situated on either side of the spine at mid-back and above the waist. They maintain salt, minerals and electrolytes in the blood, filter and remove waste products, remove excess fluid and help maintain blood pressure.

Kidney disease (renal failure or nephropathy) occurs if the kidneys are damaged by diet (particularly sugar), life choices or disease. If the kidneys are not functioning properly, waste products and fluid accumulate. With advanced kidney failure, dangerous levels of fluid and toxins build up in the body.

About 15% of Americans have chronic kidney disease. (2)

Kidney disease is usually a progressive disease that takes years to develop.

Polycystic kidney disease (PKD or polycystic kidney syndrome) is generally believed to be a genetic disorder in which the renal tubules become structurally abnormal, resulting in the development and growth of multiple cysts within the kidneys. PKD is one of the most common hereditary diseases in the USA, affecting more than 600,000 people. It is the cause of nearly 10% of all end-stage renal disease. It equally affects men, women and all races.

Symptoms of kidney disease

Causes of kidney disease

Prevention / remedies / cures / treatment for kidney disease

Until recently most doctors thought you could not do much to treat or reverse genetic diseases. However this is changing rapidly and kidney disease among many others can be treated or even reversed with diet alone. Research shows that glucose in the blood is the cause of most kidney disease.

Two recent studies done on mice found that a ketogenic diet halted and then reversed polycystic kidney disease in the mice. Kidney cysts need glucose to survive and grow. The same research found that a time-restricted diet produced a similar effect. (2, 4)

Another study using metformin to control blood glucose confirmed these effects. (5)

If you use any remedies from Grow Youthful, please come back next week (or whenever you have an outcome) and let us know about your experience. Please leave a comment as many people are interested.

See details of remedies recommended by Grow Youthful visitors, and their experience with them.

References

1. Torres JA, Rezaei M, Broderick C, Lin L, Wang X, Hoppe B, et al. Crystal deposition triggers tubule dilation that accelerates cystogenesis in polycystic kidney disease. (July 2019). The Journal of Clinical Investigation. 129 (10): 4506-4522.

2. Chronic Kidney Disease in the United States, 2021. cdc.gov. 2022-08-02.

3. Jacob A. Torres1, Samantha L. Kruger, Caroline Broderick, Tselmeg Amarlkhagva, Shagun Agrawal, John R. Dodam, Michal Mrug, Leslie A. Lyons, Thomas Weimbs. Ketosis Ameliorates Renal Cyst Growth in Polycystic Kidney Disease. Cell Metabolism. Volume 30, Issue 6, 3 December 2019, Pages 1007-1023.

4. Sienna R Li, Ramila E Gulieva, Louisa Helms, Nelly M Cruz, Thomas Vincent, Hongxia Fu, Jonathan Himmelfarb, Benjamin S Freedman. Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease. Nature Communications, 23 December 2022, volume 13, Article number: 7918.

5. Yoichi Sato, Jiahe Qiu, Takuo Hirose, Takahiro Miura, Yasunori Sato, Masahiro Kohzuki, Osamu Ito. Metformin slows liver cyst formation and fibrosis in experimental model of polycystic liver disease. Am J Physiol Gastrointest Liver Physiol, 320(4):G464-G473. 1 April 2021.