Grow Youthful: How to Slow Your Aging and Enjoy Extraordinary Health
Grow Youthful: How to Slow Your Aging and Enjoy Extraordinary Health

Cholesterol

What is cholesterol?

Cholesterol's health and healing properties

Symptoms of low cholesterol

Cholesterol sources

References

What is cholesterol?

Most animal cells can make cholesterol, but most cholesterol is made in the liver. Short chain and medium chain saturated fats are converted to ketones in the liver, and some of these ketones are used to make cholesterol. Ketones (not glucose) are also the preferred source of energy for virtually all cells in the body, including the brain.

A large part of a normal healthy human body consists of fats and cholesterol. Almost half of the walls of cells (cellular membranes) are made of cholesterol; saturated fats are another major component of all cells.

Cholesterol is one of the main healing agents in the body. When there is injury or inflammation, cholesterol is produced by the liver and sent to the site for repair work. LDL cholesterol is the form in which it is sent to do the healing at the point of inflammation. After the healing is completed, it travels back to the liver as HDL cholesterol. Cholesterol is essential for the production of healthy new cells where they are needed for repair, replacement or growth. This is why cholesterol levels rise after any injury, surgery, dental work, any kind of inflammation, or a bacterial or viral attack. After the repair work is completed, the level of blood cholesterol will naturally go down again.

The medical and pharmaceutical industries push the myth that high levels of cholesterol are dangerous, and the cause of heart disease, arterial disease, strokes and other ailments. However, this is not correct, as plenty of research shows that high levels of cholesterol are not good predictors of heart disease, (1, 2, 3, 25) the situation is just the opposite. (24, 26) Most heart attacks and strokes occur in people who do not have elevated cholesterol. Blood cholesterol levels above 6 or 7 may sometimes indicate another health condition such as liver malfunction.

The motivation for this deception is to sell statin drugs such as Lipitor, Pravachol, Crestor and Zocor. These drugs have numerous serious nasty side-effects (4, 13) such as muscle wastage, memory loss and amnesia, decreased brain function and increased risk of diabetes, and the reason for taking statins in the first place is misguided. (25, 26)

Cholesterol's health and healing properties

Cholesterol is essential for good health and wellbeing.

Symptoms of low cholesterol

Low levels of cholesterol lead to so many different ailments that it is difficult to connect the dots between the cause and the effect.

Cholesterol sources

References

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2. Jennifer G. Robinson, Neil J. Stone. Antiatherosclerotic and Antithrombotic Effects of Omega-3 Fatty Acids. The American Journal of Cardiology, 2006. 98:4, Supplement 1, 39-49.

3. Reiffel, J.A., McDonald, A. Antiarrhythmic effects of Omega-3 fatty acids. The American Journal of Cardiology. August 2006, 98 (4A): 50i-60i.doi:10.1016/j.amjcard.2005.12.027. PMID 16919517.

4. Folkers K, Langsjoen P, Willis R, Richardson P, Xia LJ, Ye CQ, Tamagawa H. Lovastatin decreases coenzyme Q levels in humans. Proc Natl Acad Sci U S A. 1990 Nov;87(22):8931-4.

5. Natasha Campbell-McBride. Put Your Heart in Your Mouth. Medinform Publishing, 2007.

6. Iribarren C. et al. Serum total cholesterol and risk of hospitalisation and death from respiratory disease. International Journal of Epidemiology 26, 1191-1202, 1997.

7. Iribarren C. et al. Cohort study of serum total cholesterol and in-hospital incidence of infectious diseases. Epidemiology and Infection 121, 335-347, 1998.

8. Elias E. R. et al. Clinical effects of cholesterol supplementation in six patients with the Smith-Lemli-Opitz syndrome (SLOS). American Journal of Medical Genetics 68, 305-310, 1997.

9. Horrobin David F. Lowering cholesterol concentrations and mortality. British Medical Journal 301, 554, 1990.

10. Chavarro JE. et al. A prospective study of dairy foods intake and anovulatory infertility. Human Reproduction, issue 28, Feb 2007.

11. Mark R. Goldstein. Do statins prevent or promote cancer? Curr Oncol. 2008 April; 15(2): 76-77.

12. L. Dupuis, et al. Dyslipidemia is a Protective Factor in Amyotropic Lateral Sclerosis. Neurology 70, no. 13 (25 March 2008): 1004-09.

13. Cholesterol-reducing Drugs May Lessen Brain Function. Science Daily, 26 February 2009, referring to Iowa State University study.

14. Rahilly-Tierney CR et al. Relation between high-density lipoprotein cholesterol and survival to age 85 years in men (from the VA Normative Aging Study). American Journal of Cardiology 2011 Apr 15;107(8):1173-7.

15. Vaarhorst AA et al. Lipid metabolism in long-lived families: the Leiden Longevity Study. Age (Dordrecht, Netherlands) 2011 Jun;33(2):219-27.

16. Williams PT. Low high-density lipoprotein 3 reduces the odds of men surviving to age 85 during 53-year follow-up. Journal of the American Geriatrics Society 2012 Mar;60(3):430-6.

17. Cheung MC et al. Phospholipid transfer protein in human plasma associates with proteins linked to immunity and inflammation. Biochemistry 2010 Aug 31;49(34):7314-22.

18. Berbee JF et al. Plasma apolipoprotein CI protects against mortality from infection in old age. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2008 Feb;63(2):122-6.

19. Han R. Plasma lipoproteins are important components of the immune system. Microbiology and Immunology 2010 Apr;54(4):246-53.

20. Gruber M et al. Prognostic impact of plasma lipids in patients with lower respiratory tract infections - an observational study. Swiss Medical Weekly 2009 Mar 21;139(11-12):166-72.

21. van Duijnhoven FJ et al. Blood lipid and lipoprotein concentrations and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition. Gut 2011 Aug;60(8):1094-102.

22. Atzmon G et al. Plasma HDL levels highly correlate with cognitive function in exceptional longevity. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2002 Nov;57(11):M712-15.

23. Cesar G Victora, Bernardo Lessa Horta, Christian Loret de Mola, Luciana Quevedo, Ricardo Tavares Pinheiro, Denise P Gigante, Helen Goncalves, Fernando C Barros. Association between breastfeeding and intelligence, educational attainment, and income at 30 years of age: a prospective birth cohort study from Brazil. The Lancet Global Health, Volume 3, No. 4, e199-e205, April 2015.

24. Hamazaki T, Okuyama H, Ogushi Y, Hama R. Towards a Paradigm Shift in Cholesterol Treatment. A Re-examination of the Cholesterol Issue in Japan. Ann Nutr Metab. 2015;66 Suppl 4:1-116. doi: 10.1159/000381654. Epub 2015 Apr 29.

25. Rafel Ramos, Marc Comas-Cufi, Ruth Marti-Lluch, Elisabeth Ballo, Anna Ponjoan, Lia Alves-Cabratosa, Jordi Blanch, Jaume Marrugat, Roberto Elosua, Maria Grau, Marc Elosua-Bayes, Luis Garcia-Ortiz, Maria Garcia-Gil. Statins for primary prevention of cardiovascular events and mortality in old and very old adults with and without type 2 diabetes: retrospective cohort study. BMJ 2018;362:k3359. Published 5 September 2018.

26. Ravnskov U, de Lorgeril M, Diamond DM, Hama R, Hamazaki T, Hammarskjold B, Hynes N, Kendrick M, Langsjoen PH, Mascitelli L, McCully KS, Okuyama H, Rosch PJ, Schersten T, Sultan S, Sundberg R. LDL-C Does Not Cause Cardiovascular Disease: a comprehensive review of current literature. Expert Rev Clin Pharmacol. 10 September 2018 (online epub). doi: 10.1080/17512433.2018.1519391.